10 selected publications

Vértesy Á, Arindrarto W, Roost MS, Reinius B, Torrens-Juaneda V, Bialecka M, Moustakas I, Ariyurek Y, Kuijk E, Mei H, Sandberg R, van Oudenaarden A*, Chuva de Sousa Lopes SM* (2018). Parental haplotype-specific single-cell transcriptomics reveal incomplete epigenetic reprogramming in human female germ cells. Nat Commun 9:1873

Roost MS, Slieker RC, Bialecka M, van Iperen L, Gomes Fernandes MM, He N, Suchiman HED, Szuhai K, Carlotti F, de Koning EJP, Mummery CL, Heijmans BT, Chuva de Sousa Lopes SM (2017). DNA methylation and transcriptional trajectories during human development and reprogramming of isogenic pluripotent stem cells. Nat Commun 8:908

Slieker RC, Roost MS, van Iperen L, Suchiman HE, Tobi EW, Carlotti F, de Koning EJ, Slagboom PE, Heijmans BT*, Chuva de Sousa Lopes SM* (2015). DNA Methylation Landscapes of Human Fetal Development. Plos Genetics e1005583

Roost MS, van Iperen L, Ariyurek Y, Buermans HP, Arindrarto W, Devalla HD, Passier R, Mummery CL, Carlotti F, de Koning EJ, van Zwet EW, Goeman JJ, Chuva de Sousa Lopes SM (2015). KeyGenes, a tool to probe tissue differentiation using a human fetal transcriptional atlas. Stem Cell Reports 4:1112-24

Takasato M, Er PX, Chiu HS, Maier B, Baillie GJ, Ferguson C, Parton RG, Wolvetang EJ, Roost MS, Chuva de Sousa Lopes SM, Little MH (2015). Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis. Nature 526:564-568

O’Leary T, Heindryckx B, Lierman S, van Bruggen D, Goeman JJ, Vandewoestyne M, Deforce D, Chuva de Sousa Lopes SM*, De Sutter P* (2012). Tracking the progression of the human inner cell mass during embryonic stem cell derivation. Nature Biotechnology 30: 778-782

Hayashi K*, Chuva de Sousa Lopes SM*, Tang F, Surani MA (2008). Dynamic equilibrium and heterogeneity of mouse pluripotent stem cells with distinct functional and epigenetic states. Cell Stem Cell 3:391-401

Cree, LM, Samuels DC, Chuva de Sousa Lopes SM, Rajasimha HK, Wonnapinij P, Mann JR, Dahl HHM, Chinnery P (2008). A reduction of mitochondrial DNA molecules during embryogenesis explains the rapid segregation of genotypes. Nature Genetics 40:249-254

Brons IG, Smithers LE, Trotter MW, Rugg-Gunn P, Sun B, Chuva de Sousa Lopes SM, Howlett SK, Clarkson A, Ahrlund-Richter L, Pedersen RA, Vallier L (2007). Derivation of pluripotent epiblast stem cells from mammalian embryos. Nature 448:191-5

Hayashi K, Chuva de Sousa Lopes SM, Surani MA (2007). Germ cell specification in mice. Science 316:394-6