2015
–
Slieker RC, Roost MS, van Iperen L, Suchiman HE, Tobi EW, Carlotti F, de Koning EJ, Slagboom PE, Heijmans BT*, Chuva de Sousa Lopes SM* (2015). DNA Methylation Landscapes of Human Fetal Development. Plos Genet e1005583
Takasato M, Er PX, Chiu HS, Maier B, Baillie GJ, Ferguson C, Parton RG, Wolvetang EJ, Roost MS, Chuva de Sousa Lopes SM, Little MH (2015). Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis. Nature 526:564-568
Locher H, de Groot JC, van Iperen L, Huisman MA, Frijns JH, Chuva de Sousa Lopes SM (2015). Development of the stria vascularis and potassium regulation in the human fetal cochlea: Insights into hereditary sensorineural hearing loss. Dev Neurobiol 75:1219-1240
van den Berg CW, Okawa S, Chuva de Sousa Lopes SM, van Iperen L, Passier R, Braam SR, Tertoolen LG, Del Sol A, Davis RP, Mummery CL (2015). Transcriptome of human foetal heart compared with cardiomyocytes from pluripotent stem cells. Development 142:3231-3238
Duggal G, Warrier S, Ghimire S, Broekaert D, Van der Jeught M, Lierman S, Deroo T, Peelman L, Van Soom A, Cornelissen R, Menten B, Mestdagh P, Vandesompele J, Roost M, Slieker RC, Heijmans BT, Deforce D, De Sutter P, De Sousa Lopes SC*, Heindryckx B* (2015). Alternative routes to induce naïve pluripotency in human embryonic stem cells. Stem Cells 33:2686-2698
Crisan M, Kartalaei PS, Vink C, Yamada-Inagawa T, Bollerot K, van IJcken W, van der Linden R, de Sousa Lopes SM, Monteiro R, Mummery C, Dzierzak E (2015). BMP signalling differentially regulates distinct haematopoietic stem cell types. Nat Commun 6:8040
de Melo Bernardo A, Heeren AM, van Iperen L, Fernandes MG, He N, Anjie S, Noce T, Ramos ES, de Sousa Lopes SM (2015). Meiotic wave adds extra asymmetry to the development of female chicken gonads. Mol Reprod Dev 82:774-786
Van der Jeught M, O’Leary T, Duggal G, De Sutter P, Chuva de Sousa Lopes S*, Heindryckx B* (2015). The post-inner cell mass intermediate: implications for stem cell biology and assisted reproductive technology. Hum Reprod Update 21:616-626
Van der Jeught M, Taelman J, Duggal G, Ghimire S, Lierman S, Chuva de Sousa Lopes SM, Deforce D, Deroo T, De Sutter P, Heindryckx B (2015). Application of small molecules favoring naïve pluripotency during human embryonic stem cell derivation. Cell Reprogram17:170-180
Roost MS, van Iperen L, Ariyurek Y, Buermans HP, Arindrarto W, Devalla HD, Passier R, Mummery CL, Carlotti F, de Koning EJ, van Zwet EW, Goeman JJ, Chuva de Sousa Lopes SM (2015). KeyGenes, a tool to probe tissue differentiation using a human fetal transcriptional atlas. Stem Cell Rep 4:1112-24
Kugler J, Tharmann J, Chuva de Sousa Lopes SM, Kemler R, Luch A, Oelgeschläger M (2015). A Bmp reporter transgene mouse embryonic stem cell model as a tool to identify and characterize chemical teratogens. Toxicol Sci 146:374-385
Duggal G, Heindryckx B, Warrier S, Taelman J, Van der Jeught M, Deforce D, Chuva de Sousa Lopes S*, De Sutter P* (2015). Exogenous supplementation of Activin A enhances germ cell differentiation of human embryonic stem cells. Mol Hum Reprod 21:410-423
Sugimoto M, Kondo M, Koga Y, Shiura H, Ikeda R, Hirose M, Ogura A, Murakami A, Yoshiki A, Chuva de Sousa Lopes SM, Abe K (2015). A Simple and Robust Method for Establishing Homogeneous Mouse Epiblast Stem Cell Lines by Wnt Inhibition. Stem Cell Rep 4:744-757
Roovers EF, Rosenkranz D, Mahdipour M, Han CT, He N, Chuva de Sousa Lopes SM, van der Westerlaken LA, Zischler H, Butter F, Roelen BA, Ketting RF (2015). Piwi Proteins and piRNAs in Mammalian Oocytes and Early Embryos. Cell Rep 10:2069-2082
Devalla HD, Schwach V, Ford JW, Milnes JT, El-Haou S, Jackson C, Gkatzis K, Elliott DA, Chuva de Sousa Lopes SM, Mummery CL, Verkerk AO, Passier R (2015). Atrial-like cardiomyocytes from human pluripotent stem cells are a robust preclinical model for assessing atrial-selective pharmacology. EMBO Mol Med 7:394-410
Heeren A, van Iperen L, Klootwijk DB, de Melo Bernardo A, Roost MS, Gomes Fernandes MM, Louwe LA, Hilders CG, Helmerhorst FM, van der Westerlaken LA, Chuva de Sousa Lopes SM (2015). Development of the follicular basement membrane during human gametogenesis and early folliculogenesis. BMC Dev Biol 15:4
Chuva de Sousa Lopes SM, Roelen BAJ (2015). Current status of in vitro differentiation of stem cells into gametes. Animal Reprod 12:46-51
Ghimire S, Heindryckx B, Van der Jeught M, Neupane J, O’Leary T, Lierman S, De Vos WH, Chuva de Sousa Lopes S, Deroo T, De Sutter P (2015). Inhibition of TGFβ signalling promotes epiblast formation in mouse embryos. Stem Cells Dev 24:497-506
2014
–
Cajal M, Creuzet SE, Papanayotou C, Sabéran-Djoneidi D, Chuva de Sousa Lopes SM, Zwijsen A, Collignon J, Camus A (2014). A conserved role for non-neural ectoderm cells in early neural development. Development 141:4127-4138.
Locher H, Frijns JHM, Huisman MA, Chuva de Sousa Lopes SM (2014). TUBB3: Neuronal marker or melanocyte mimic? Cell Transplantation 23:1471-1473.
Machado FB, Machado FB, Faria MA, Lovatel VL, Alves da Silva AF, Radic CP, De Brasi CD, Rios AF, Chuva de Sousa Lopes SM, da Silveira LS, Ruiz-Miranda CR, Ramos ES, Medina-Acosta E (2014). 5meCCpG epigenetic marks neighboring a primate-conserved core promoter short tandem repeat indicate X-chromosome inactivation. Plos One 9:e103714.
De Melo Bernardo A, Chuva de Sousa Lopes SM (2014). The involvement of the proamnion in the development of the anterior amnion fold in the chicken. Plos One 9:e92672.
Locher H, de Groot JC, van Iperen L, Huisman MA, Frijns JH, Chuva de Sousa Lopes SM (2014). Distribution and development of peripheral glial cells in the human fetal cochlea. Plos One 9:e88066.
Caetano LC, Gennaro FGO, Coelho KC, Araujo FM, Villa RA, Oliveira AA, De Melo Bernardo A, Marcondes CR, Paz CCP, Chuva de Sousa Lopes SM, Ramos ES (2014). Differential expression of MHM region and sex–determining-related genes during gonadal development in chicken embryos. Genetics and Molecular Research 13:838-849.
Van der Jeught, Heindryckx B, O’Leary T, Duggal G, Ghimire S, Lierman S, Van Roy N, Chuva de Sousa Lopes SM, Deroo T, Deforce D, De Sutter P (2014). Treatment of human embryos with the TGFβ inhibitor SB431542 increases epiblast proliferation and permits successful human embryonic stem cell derivation. Human Reproduction 29:41-48.
2013
–
Locher H, Frijns JHM, van Iperen L, de Groot JCMJ, Huisman MA, Chuva de Sousa Lopes SM (2013). Neurosensory development and cell fate determination in the human cochlea. Neural Development 8:20.
Duggal G, Heindryckx B, Warrier S, O’Leary T, Van der Jeught M, Lierman S, Vossaert L, Deroo T, Deforce D, Chuva de Sousa Lopes SM*, De Sutter P* (2013). Influence of Activin A Supplementation During Human Embryonic Stem Cell Derivation on Germ Cell Differentiation Potential. Stem Cells Dev., 22:3141-3145.
Locher H, de Rooij KE, de Groot JC, Doorn RV, Gruis NA, Löwik CW, Chuva de Sousa Lopes SM, Frijns JH, Huisman MA (2013). Class III β-tubulin, a novel biomarker in the human melanocyte lineage. Differentiation 85:173-181.
O’Leary T, Heindryckx B, Lierman S, Van der Jeught M, Duggal G, De Sutter P*, Chuva de Sousa Lopes SM* (2013). Derivation of human embryonic stem cells using a post-inner cell mass intermediate. Nature Protocols 8, 254-264.
Van der Jeught M, O’Leary T, Ghimire S, Lierman S, Duggal G, Versieren K, Deforce D, Chuva de Sousa Lopes SM, Heindryckx B, De Sutter P (2013). The combination of inhibitors of FGF/MEK/Erk and GSK3β signaling increases the number of OCT3/4- and NANOG-positive cells in the human inner cell mass, but does not improve stem cell derivation. Stem Cells Dev. 22, 296-306.
2012
–
De Melo Bernardo A, Sprenkels K, Rodrigues G, Noce T, Chuva de Sousa Lopes SM (2012). Chicken primordial germ cells use the anterior vitelline veins to enter the embryonic circulation. Biol. Open 1, 1146-52.
Bialecka M, Young T, Chuva de Sousa Lopes SM, ten Berge D, Sanders A, Beck F, Deschamps J (2012). Cdx2 contributes to the expansion of the early primordial germ cell population in the mouse. Dev. Biol. 371, 227-34.
Versieren K, Van der Jeught M, O’Leary T, Duggal G, Gerris J, Chuva de Sousa Lopes SM, Heindryckx B, De Sutter P (2012). Effect of small molecule supplements during in vitro culture of mouse zygotes and parthenogenetic embryos on hypoblast formation and stem cell derivation. Stem Cell Rev. 8, 1088-97.
Sountoulidis A, Stavropoulos A, Giaglis S, Apostolou E, Monteiro R, Chuva de Sousa Lopes SM, Chen H, Stripp BR, Mummery C, Andreakos E, Sideras P (2012). Activation of the Canonical Bone Morphogenetic Protein (BMP) Pathway during Lung Morphogenesis and Adult Lung Tissue Repair. PLoS ONE 7, e41460.
Dobreva MP, Lhoest L, Pereira PN, Umans L, Chuva de Sousa Lopes SM, Zwijsen A (2012). Periostin as a biomarker of the amniotic membrane. Stem Cells Int. 2012, 987185.
Pereira PN, Dobreva MP, Maas E, Cornelis FM, Moya IM, Umans L, Verfaillie CM, Camus A, de Sousa Lopes SM, Huylebroeck D, Zwijsen A (2012). Antagonism of Nodal signaling by BMP/Smad5 prevents ectopic primitive streak formation in the mouse amnion. Development 139, 3343-54.
Teklenburg G, Weimar CHE, Fauser BCJ, Macklon N, Geijsen N, Heijnen CJ, Chuva de Sousa Lopes SM, Kuijk EW (2012). Cell lineage specific distribution of H3K27 trimethylation accumulation in an in vitro model for human implantation. PLoS One, 7, e32701.
O’Leary T, Heindryckx B, Lierman S, van Bruggen D, Goeman JJ, Vandewoestyne M, Deforce D, Chuva de Sousa Lopes SM*, De Sutter P* (2012). Tracking the progression of the human inner cell mass during embryonic stem cell derivation. Nature Biotech., 30, 778-782.
2011
–
Roelen BA, Chuva de Sousa Lopes, SM (2011). Origins of pluripotent stem cells. Minerva Ginecol. 63:351-63.
Leeuwis JW, Nguyen TQ, Chuva de Sousa Lopes SM, van der Giezen DM, van der Ven K, Rouw PJ, Offerhaus GJ, Mummery CL, Goldschmeding R (2011).
Direct visualization of Smad1/5/8-mediated transcriptional activity identifies podocytes and collecting ducts as major targets of BMP signalling in healthy and diseased kidneys. J. Pathol., 224,121-132.
Roelen BA, Chuva de Sousa Lopes SM (2011). 1st Royan Institute International Summer School on Developmental Biology and Stem Cells. Tehran, 12-15 July 2010. Int. J. Dev. Biol., 55:1-4.
Chuva de Sousa Lopes SM, Roelen BAJ (2011). The way of the germline, its developmental cycle and epigenetic network. Differentiation, 81, 217-221.
O’Leary T, Heindryckx B, Lierman S, Van der Jeught M, Menten B, Deforce D, Cornelissen M, Chuva de Sousa Lopes SM, De Sutter P (2011). The influence of early embryo traits on human embryonic stem cell derivation efficiency. Stem Cells Dev., 20, 785-793.
Puy LD, Chuva de Sousa Lopes SM, Haagsman HP, Roelen BA. (2011). Analysis of co-expression of OCT4, NANOG and SOX2 in pluripotent cells of the porcine embryo, in vivo and in vitro. Theriogenology, 75, 513-526.
Kuijk EW, Chuva de Sousa Lopes SM, Geijsen N, Macklon N, Roelen BAJ (2011). The different shades of mammalian pluripotent stem cells. Hum. Reprod. Update, 17, 254-271.