2006 – 2010


Kuijk EW, de Gier J, Chuva de Sousa Lopes SM, Chambers I, van Pelt AM, Colenbrander B, Roelen BAJ (2010). A distinct expression pattern in mammalian testes indicates a conserved role for NANOG in spermatogenesis. PLoS One, 5, e10987.

Chuva de Sousa Lopes SM, Roelen BAJ (2010). On the formation of germ cells: The good, the bad and the ugly. Differentiation, 79, 131-140.

Chuva de Sousa Lopes SM, Roelen BAJ (2010). An overview of the diversity of cellular organelles during the germ cell cycle. Histol. Histopathol., 25, 267-276.

Villaconte M, Suzuki K, Hayashi K, de Sousa-Lopes SM, Haraguchi R, Taketo M, Nakagata N, Yamada G (2010).
Antagonistic crosstalk of Wnt/beta-catenin/BMP signalling within the Apical Ectodermal Ridge (AER) regulates interdigit formation. Biochem. Bioph. Res. Co., 391, 1653-7.

du Puy L, Chuva de Sousa Lopes SM, Haagsman H, Roelen B (2010). Differentiation of porcine inner cell mass cells into proliferating neural cells. Stem Cells Dev., 19, 61-70.



Nijmeijer RM, Leeuwis JW, DeLisio A, Mummery CL, Chuva de Sousa Lopes SM (2009). Visceral endoderm induces specification of cardiomyocytes in mice. Stem Cell Res., 3, 170-8.



Hayashi K*, Chuva de Sousa Lopes SM*, Tang F, Surani MA (2008). Dynamic equilibrium and heterogeneity of mouse pluripotent stem cells with distinct functional and epigenetic states. Cell Stem Cell, 3, 391-401.

Chuva de Sousa Lopes SM, Roelen BAJ (2008). Primordial germ cell specification: the importance of being “blimped”. Histol. Histopathol., 23, 1553-1561.

Chuva de Sousa Lopes SM*, Monteiro RM*, Bialecka M, de Boer S, Zwijsen A, Mummery C (2008).
Real time monitoring of BMP Smad transcriptional activity during mouse development. Genesis, 46, 335-346.

Roelen BAJ, Chuva de Sousa Lopes SM (2008). Of stem cells and gametes: similarities and differences.
Curr. Med. Chem., 15, 1249-1256.

Chuva de Sousa Lopes SM, Hayashi K, Shovlin T, Mifsud W, Surani MA, McLaren A (2008). X chromosome activity in mouse XX primordial germ cells. PLoS Genetics, 4, e30.

Hayashi K, Chuva de Sousa Lopes SM, Kaneda M, Tang F, Hajkova P, Lao K, O’Carroll, Das PP, Tarakhovsky A, Miska EA, Surani MA (2008). MicroRNA biogenesis is required for mouse primordial germ cell development and spermatogenesis. PLoS one, 3, e1738.

Cree, LM, Samuels DC, Chuva de Sousa Lopes SM, Rajasimha HK, Wonnapinij P, Mann JR, Dahl HHM, Chinnery P (2008). A reduction of mitochondrial DNA molecules during embryogenesis explains the rapid segregation of genotypes. Nature Genetics, 40, 249-254.



Chuva de Sousa Lopes SM, Hayashi K, Surani MA (2007). Proximal visceral endoderm and extraembryonic ectoderm regulate the formation of primordial germ cell precursors. BMC Dev. Biol., 7, 140-149.

Brons IG, Smithers LE, Trotter MW, Rugg-Gunn P, Sun B, Chuva de Sousa Lopes SM, Howlett SK, Clarkson A, Ahrlund-Richter L, Pedersen RA, Vallier L (2007). Derivation of pluripotent epiblast stem cells from mammalian embryos. Nature, 448, 191-5.

Hayashi K, Chuva de Sousa Lopes SM, Surani MA (2007). Germ cell specification in mice. Science, 316, 394-6.



de Bruijn DRH, Peters WJM, Chuva de Sousa Lopes SM, van Dijk AHA, Willemse MP, Pfundt R, de Boer P, Geurts van Kessel A (2006). Targeted disruption of the synovial sarcoma-associated protein SS18 gene causes early embryonic lethality and affects PPARBP expression. Hum. Mol. Genet., 15, 2936-2944.

Chuva de Sousa Lopes SM*, Hassink RJ*, Feijen A, van Rooijen MA, Doevendans PA, Tertoolen L, Brutel de la Riviere A, Mummery CL (2006). Patterning the heart, a template for human cardiomyocyte development. Dev. Dynam., 235, 1994-2002.

Payer B, Chuva de Sousa Lopes SM, Barton SC, Lee C, Saitou M, Surani MA (2006).
Generation of stella-GFP transgenic mice, a novel tool to study germ cell development. Genesis, 44, 75-83.